| Date/Time | Away | Home | Line | ||||
|---|---|---|---|---|---|---|---|
| Byes: none | |||||||
| 1. | Thu, Nov. 20,8:15 PM | Cincinnati (1-8-1) | 10 | 27 | Pittsburgh (7-3) | -10.5 (34) | |
| 2. | Sun, Nov. 23,1:00 PM | Philadelphia (5-4-1) | 7 | 36 | Baltimore (6-4) | -1 (40) | |
| 3. |
|
Houston (3-7) | 16 | 6 | Cleveland (4-6) | -3 (50) | |
| 4. |
|
San Francisco (3-7) | 22 | 35 | Dallas (6-4) | -10.5 (46.5) | |
| 5. |
|
Tampa Bay (7-3) | 38 | 20 | Detroit (0-10) | +8.5 (41) | |
| 6. |
|
Minnesota (5-5) | 30 | 12 | Jacksonville (4-6) | -2.5 (40.5) | |
| 7. |
|
Buffalo (5-5) | 54 | 31 | Kansas City (1-9) | +3 (43.5) | |
| 8. |
|
New England (6-4) | 48 | 28 | Miami (6-4) | -2 (42) | |
| 9. |
|
Chicago (5-5) | 27 | 3 | St. Louis (2-8) | +8.5 (43) | |
| 10. |
|
N.Y. Jets (7-3) | 34 | 13 | Tennessee (10-0) | -5 (40.5) | |
| 11. | Sun, Nov. 23,4:05 PM | Oakland (2-8) | 31 | 10 | Denver (6-4) | -9.5 (42.5) | |
| 12. | Sun, Nov. 23,4:15 PM | N.Y. Giants (9-1) | 37 | 29 | Arizona (7-3) | +3 (49) | |
| 13. |
|
Carolina (8-2) | 28 | 45 | Atlanta (6-4) | -1 (42.5) | |
| 14. |
|
Washington (6-4) | 20 | 17 | Seattle (2-8) | +3.5 (40.5) | |
| 15. | Sun, Nov. 23,8:15 PM | Indianapolis (6-4) | 23 | 20 | San Diego (4-6) | -3 (49.5) | |
| 16. | Mon, Nov. 24,8:30 PM | Green Bay (5-5) | 29 | 51 | New Orleans (5-5) | -2.5 (51.5) | |
All times are Eastern Standard Time.