| Date/Time | Away | Home | Line | ||||
|---|---|---|---|---|---|---|---|
| Byes: none | |||||||
| 1. | Thu, Nov. 27,12:30 PM | Tennessee (10-1) | 47 | 10 | Detroit (0-11) | +7 (22.5) | |
| 2. | Thu, Nov. 27,4:15 PM | Seattle (2-9) | 9 | 34 | Dallas (7-4) | -7 (23.5) | |
| 3. | Thu, Nov. 27,8:15 PM | Arizona (7-4) | 20 | 48 | Philadelphia (5-5-1) | -1 (23.5) | |
| 4. | Sun, Nov. 30,1:00 PM | San Francisco (3-8) | 10 | 3 | Buffalo (6-5) | -7 (42.5) | |
| 5. |
|
Baltimore (7-4) | 34 | 3 | Cincinnati (1-9-1) | +7 (36.5) | |
| 6. |
|
Indianapolis (7-4) | 10 | 6 | Cleveland (4-7) | +4.5 (45) | |
| 7. |
|
Carolina (8-3) | 35 | 31 | Green Bay (5-6) | -3 (43) | |
| 8. |
|
Miami (6-5) | 16 | 12 | St. Louis (2-9) | +7.5 (43.5) | |
| 9. |
|
New Orleans (6-5) | 20 | 23 | Tampa Bay (8-3) | -3.5 (47.5) | |
| 10. |
|
N.Y. Giants (10-1) | 23 | 7 | Washington (7-4) | +3.5 (41.5) | |
| 11. | Sun, Nov. 30,4:05 PM | Atlanta (7-4) | 22 | 16 | San Diego (4-7) | -5 (49) | |
| 12. | Sun, Nov. 30,4:15 PM | Pittsburgh (8-3) | 33 | 10 | New England (7-4) | -1 (40) | |
| 13. |
|
Denver (6-5) | 34 | 17 | N.Y. Jets (8-3) | -8 (47.5) | |
| 14. |
|
Kansas City (1-10) | 20 | 13 | Oakland (3-8) | -3 (41.5) | |
| 15. | Sun, Nov. 30,8:15 PM | Chicago (6-5) | 14 | 34 | Minnesota (6-5) | -3.5 (42) | |
| 16. | Mon, Dec. 1,8:30 PM | Jacksonville (4-7) | 17 | 30 | Houston (4-7) | -3 (48) | |
All times are Eastern Standard Time.